The Application of NHEJ-CRISPR/Cas9 and Cre-Lox System in the Generation of Bivalent Duck Enteritis Virus Vaccine against Avian Influenza Virus

The Application of NHEJ-CRISPR/Cas9 and Cre-Lox System in the Generation of Bivalent Duck Enteritis Virus Vaccine against Avian Influenza Virus

Duck-targeted vaccines to protect against avian influenza are critically needed to aid in influenza disease control efforts in regions where ducks are endemic for highly pathogenic avian influenza (HPAI). Duck enteritis virus (DEV) is a promising candidate viral vector for development of vaccines ta...

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Bibliographic Details
Main Authors: Pengxiang Chang, Yongxiu Yao, Na Tang, Jean-Remy Sadeyen, Joshua Sealy, Anabel Clements, Sushant Bhat, Muhammad Munir, Juliet E. Bryant, Munir Iqbal
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Viruses
Subjects:
duck enteritis virus
CRISPR/Cas9
NHEJ
influenza
Cre
Lox
Online Access:http://www.mdpi.com/1999-4915/10/2/81

Internet

http://www.mdpi.com/1999-4915/10/2/81

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