Optimization of tetramycin production in Streptomyces ahygroscopicus S91

Abstract Background Tetramycin is a 26-member tetraene antibiotic used in agriculture. It has two components, tetramycin A and tetramycin B. Tetramycin B is obtained by the hydroxylation of tetramycin A on C4. This reaction is catalyzed by the cytochrome P450 monooxygenase TtmD. The two components o...

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Bibliographic Details
Main Authors: Guang Chen, Mengqiu Wang, Xianpu Ni, Huanzhang Xia
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-021-00267-4