Optimization of tetramycin production in Streptomyces ahygroscopicus S91
Abstract Background Tetramycin is a 26-member tetraene antibiotic used in agriculture. It has two components, tetramycin A and tetramycin B. Tetramycin B is obtained by the hydroxylation of tetramycin A on C4. This reaction is catalyzed by the cytochrome P450 monooxygenase TtmD. The two components o...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | Journal of Biological Engineering |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13036-021-00267-4 |