Human norovirus targets enteroendocrine epithelial cells in the small intestine

Human norovirus targets enteroendocrine epithelial cells in the small intestine

Human norovirus pathogenesis is incompletely understood due to a lack of appropriate animal disease models. Here, Green et al. show norovirus replication in chromogranin A-positive enteroendocrine cells and other epithelial cells in tissue from a pediatric intestinal transplant recipient with severe...

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Bibliographic Details
Main Authors: Kim Y. Green, Stuart S. Kaufman, Bianca M. Nagata, Natthawan Chaimongkol, Daniel Y. Kim, Eric A. Levenson, Christine M. Tin, Allison Behrle Yardley, Jordan A. Johnson, Ana Beatriz F. Barletta, Khalid M. Khan, Nada A. Yazigi, Sukanya Subramanian, Sangeetha R. Moturi, Thomas M. Fishbein, Ian N. Moore, Stanislav V. Sosnovtsev
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16491-3

Internet

https://doi.org/10.1038/s41467-020-16491-3

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