Molecular bases of cellular senescence: Hayflick phenomenon 50 years later

Normal human somatic cells have strictly limited proliferative capacity and reach a state of senescence when it becomes exhausted. It is believed that senescence is a response to extensive and irreparable DNA injury, localized in telomeric and/or non-telomeric regions of the genome. Main cause of th...

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Bibliographic Details
Main Authors: Patrycja Sosińska, Justyna Mikuła-Pietrasik, Krzysztof Książek
Format: Article
Language:English
Published: Index Copernicus International S.A. 2016-03-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Online Access:http://phmd.pl/gicid/01.3001.0009.6803