Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy

Abstract Since CRISPR/Cas9 was harnessed to edit DNA, the field of gene therapy has witnessed great advances in gene editing. New avenues were created for the treatment of diseases such as Cystic Fibrosis (CF). CF is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFT...

Full description

Bibliographic Details
Main Authors: Ranmal Avinash Bandara, Ziyan Rachel Chen, Jim Hu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-021-00662-w