Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures

Understanding of the mycobacterial transcription system is useful to the development of therapeutics against tuberculosis infection. Here the authors present the crystal structure of a completeM. smegmatisRNA polymerase open promoter complex that reveals unique features of the mycobacterial polymera...

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Bibliographic Details
Main Authors: Elizabeth A. Hubin, Mirjana Lilic, Seth A. Darst, Elizabeth A. Campbell
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms16072