Epigenetic Suppression of the T-box Subfamily 2 (TBX2) in Human Non-Small Cell Lung Cancer

Epigenetic Suppression of the T-box Subfamily 2 (TBX2) in Human Non-Small Cell Lung Cancer

(1) The TBX2 subfamily of transcription factors (TBXs 2, 3, 4 and 5) are markedly down-regulated in human non-small cell lung cancer (NSCLC) and exert tumor suppressor effects in lung malignancy. Yet, mechanisms underlying suppressed expression of the TBX2 subfamily in NSCLC are elusive. Here, we in...

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Bibliographic Details
Main Authors: Eliana Nehme, Zahraa Rahal, Ansam Sinjab, Athar Khalil, Hassan Chami, Georges Nemer, Humam Kadara
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
non-small cell lung cancer
TBX2
epigenetic suppression
methylation
Online Access:http://www.mdpi.com/1422-0067/20/5/1159

Internet

http://www.mdpi.com/1422-0067/20/5/1159

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