Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily

Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily

The human genome encodes about 285 proteins that contain at least one annotated pleckstrin homology (PH) domain. As the first phosphoinositide binding module domain to be discovered, the PH domain recruits diverse protein architectures to cellular membranes. PH domains constitute one of the largest...

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Bibliographic Details
Main Authors: Marc Lenoir, Irina Kufareva, Ruben Abagyan, Michael Overduin
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Membranes
Subjects:
bilayer insertion
lipid binding
membrane trafficking
MODA
peripheral membrane protein
PH domain
phosphoinositide recognition
plasma membrane
pleckstrin homology domain
small GTPase
Online Access:http://www.mdpi.com/2077-0375/5/4/646

Internet

http://www.mdpi.com/2077-0375/5/4/646

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