The anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress.

The anaphase-promoting complex or cyclosome (APC/C) is a multi-subunit ubiquitin ligase that regulates exit from mitosis and G1 phase of the cell cycle. Although the regulation and function of APC/C(Cdh1) in the unperturbed cell cycle is well studied, little is known of its role in non-genotoxic str...

Full description

Bibliographic Details
Main Authors: Meifan Chen, Gustavo J Gutierrez, Ze'ev A Ronai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335095?pdf=render