Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation

Glioblastoma multiforme (GBM) is the most common and malignant type of central nervous system tumours in adults. Strict regulation of glucose homeostasis has a significant role in GBM pathogenesis. Insulin receptor substrate 1 (IRS1) protein is the most important adaptor molecule involved in the reg...

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Bibliographic Details
Main Authors: Gokhan Gorgisen, Zafer Yaren
Format: Article
Language:English
Published: Termedia Publishing House 2020-03-01
Series:Folia Neuropathologica
Subjects:
gbm
Online Access:https://www.termedia.pl/Insulin-receptor-substrate-1-overexpression-promotes-survival-of-glioblastoma-cells-through-AKT1-activation,20,40220,1,1.html