DIP/Dpr interactions and the evolutionary design of specificity in protein families

DIP/Dpr interactions and the evolutionary design of specificity in protein families

Dpr (Defective proboscis extension response) and DIP (Dpr Interacting Proteins) are immunoglobulin-like cell-cell adhesion proteins that form highly specific pairwise interactions, which control synaptic connectivity during Drosophila development. Here, the authors combine a computational approach w...

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Bibliographic Details
Main Authors: Alina P. Sergeeva, Phinikoula S. Katsamba, Filip Cosmanescu, Joshua J. Brewer, Goran Ahlsen, Seetha Mannepalli, Lawrence Shapiro, Barry Honig
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15981-8

Internet

https://doi.org/10.1038/s41467-020-15981-8

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