Layer- and column-specific knockout of NMDA receptors in pyramidal neurons of the mouse barrel cortex.

Viral vectors injected into the mouse brain offer the possibility for localized genetic modifications in a highly controlled manner. Lentivector injection into mouse neocortex transduces cells within a diameter of approximately 200µm, which closely matches the lateral scale of a column in...

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Bibliographic Details
Main Authors: Rachel Aronoff, Carl Petersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2007-11-01
Series:Frontiers in Integrative Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.07.001.2007/full