Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis.

Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis.

Heme oxygenase 1 (HMOX1) is the rate limiting enzyme in heme degradation and a key regulator of inflammatory processes. In animal models the course of pancreatitis was ameliorated by up-regulation of HMOX1 expression. Additionally, carbon monoxide released during heme breakdown inhibited proliferati...

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Bibliographic Details
Main Authors: Sebastian Weis, Moritz Jesinghaus, Peter Kovacs, Dorit Schleinitz, Robert Schober, Claudia Ruffert, Max Herms, Henning Wittenburg, Michael Stumvoll, Matthias Blüher, Robert Grützmann, Hans-Ulrich Schulz, Volker Keim, Joachim Mössner, Peter Bugert, Heiko Witt, Joost P H Drenth, Knut Krohn, Jonas Rosendahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364204?pdf=render

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http://europepmc.org/articles/PMC3364204?pdf=render

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