RSP5 Positively Regulates the Osteogenic Differentiation of Mesenchymal Stem Cells by Activating the K63-Linked Ubiquitination of Akt

Mesenchymal stem cells (MSCs) are multipotent stem cells that have a strong osteogenic differentiation capacity. However, the molecular mechanism underlying the osteogenic differentiation of MSCs remains largely unknown and thus hinders further development of MSC-based cell therapies for bone repair...

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Bibliographic Details
Main Authors: Changxiang Liang, Guoyan Liang, Xiaoqing Zheng, Yongxiong Huang, Shuaihao Huang, Dong Yin
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2020/7073805