Influence of Intermittent Hypoxia/Hypercapnia on Atherosclerosis, Gut Microbiome, and Metabolome

Obstructive sleep apnea (OSA), a common sleep disorder characterized by intermittent hypoxia and hypercapnia (IHC), increases atherosclerosis risk. However, the contribution of intermittent hypoxia (IH) or intermittent hypercapnia (IC) in promoting atherosclerosis remains unclear. Since gut microbio...

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Bibliographic Details
Main Authors: Jin Xue, Celeste Allaband, Dan Zhou, Orit Poulsen, Cameron Martino, Lingjing Jiang, Anupriya Tripathi, Emmanuel Elijah, Pieter C. Dorrestein, Rob Knight, Amir Zarrinpar, Gabriel G. Haddad
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.663950/full