RNase L Induces Expression of A Novel Serine/Threonine Protein Kinase, DRAK1, to Promote Apoptosis

Apoptosis of virus-infected cells is an effective antiviral mechanism in addition to interferon induction to establish antiviral state to restrict virus spread. The interferon-inducible 2′−5′ oligoadenylate synthetase/RNase L pathway results in activation of RNase L in...

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Bibliographic Details
Main Authors: Praveen Manivannan, Vidita Reddy, Sushovita Mukherjee, Kirsten Neytania Clark, Krishnamurthy Malathi
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
JNK
Online Access:https://www.mdpi.com/1422-0067/20/14/3535