Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy

Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy

Dietary PUFAs reduce atherosclerosis and macrophage inflammation, but how nucleotide-binding oligomerization domain leucine-rich repeat-containing receptor protein (NLRP3) inflammasome activation and autophagy influence PUFA-mediated atheroprotection is poorly understood. We fed Ldlr−/− mice diets c...

Full description

Bibliographic Details
Main Authors: Lulu Shen, Yan Yang, Tiantong Ou, Chia-Chi C. Key, Sarah H. Tong, Russel C. Sequeira, Jonathan M. Nelson, Yan Nie, Zhan Wang, Elena Boudyguina, Swapnil V. Shewale, Xuewei Zhu
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Lipid Research
Subjects:
inflammation
atherosclerosis
omega-3 fatty acids
fish oil
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339523

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520339523

Similar Items