Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis

Herpesviruses code for conserved protein kinases (CHPKs) that exert several regulatory functions by interacting with cellular factors. Here, the authors use affinity purification mass spectrometry (AP–MS) to identify differential interaction partners of CHPKs from seven different human herpesviruses...

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Bibliographic Details
Main Authors: Boris Bogdanow, Max Schmidt, Henry Weisbach, Iris Gruska, Barbara Vetter, Koshi Imami, Eleonore Ostermann, Wolfram Brune, Matthias Selbach, Christian Hagemeier, Lüder Wiebusch
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18542-1