AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro.

Epileptic seizures are frequent in patients with glioblastoma, and anticonvulsive treatment is often necessary. While clinical guidelines recommend all approved anticonvulsants, so far it is still unclear which of the available drugs is the best therapeutic option for treating glioma-associated seiz...

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Bibliographic Details
Main Authors: Falko Lange, Konrad Weßlau, Katrin Porath, Julia Hörnschemeyer, Carina Bergner, Bernd Joachim Krause, Christina Susanne Mullins, Michael Linnebacher, Rüdiger Köhling, Timo Kirschstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211644