Unusual Glycosaminoglycans from a Deep Sea Hydrothermal Bacterium Improve Fibrillar Collagen Structuring and Fibroblast Activities in Engineered Connective Tissues

Unusual Glycosaminoglycans from a Deep Sea Hydrothermal Bacterium Improve Fibrillar Collagen Structuring and Fibroblast Activities in Engineered Connective Tissues

Biopolymers produced by marine organisms can offer useful tools for regenerative medicine. Particularly, HE800 exopolysaccharide (HE800 EPS) secreted by a deep-sea hydrothermal bacterium displays an interesting glycosaminoglycan-like feature resembling hyaluronan. Previous studies demonstrated its e...

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Bibliographic Details
Main Authors: Jean Guezennec, Gaston Godeau, Didier Lutomski, Jacqueline Ratiskol, Corinne Sinquin, Dominique Septier, Sylvie Changotade, Farida Gueniche, Karim Senni, Sylvia Colliec-Jouault
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Marine Drugs
Subjects:
marine hydrothermal bacteria
glycosaminoglycan-mimetic
collagen
matrix metalloproteinases
dermal fibroblast
polysaccharides
tissue engineering
Online Access:http://www.mdpi.com/1660-3397/11/4/1351

Internet

http://www.mdpi.com/1660-3397/11/4/1351

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