Small-angle X-ray scattering reveals compact domain-domain interactions in the N-terminal region of filamin C.

Filamins are multi-domain, actin cross-linking, and scaffolding proteins. In addition to the actin cross-linking function, filamins have a role in mechanosensor signaling. The mechanosensor function is mediated by domain-domain interaction in the C-terminal region of filamins. Recently, we have show...

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Bibliographic Details
Main Authors: Ritika Sethi, Jari Ylänne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4170960?pdf=render