Hydroxyurea-Increased Fetal Hemoglobin Is Associated with Less Organ Damage and Longer Survival in Adults with Sickle Cell Anemia.

<h4>Background</h4>Adults with sickle cell anemia (HbSS) are inconsistently treated with hydroxyurea.<h4>Objectives</h4>We retrospectively evaluated the effects of elevating fetal hemoglobin with hydroxyurea on organ damage and survival in patients enrolled in our screening s...

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Bibliographic Details
Main Authors: Courtney D Fitzhugh, Matthew M Hsieh, Darlene Allen, Wynona A Coles, Cassie Seamon, Michael Ring, Xiongce Zhao, Caterina P Minniti, Griffin P Rodgers, Alan N Schechter, John F Tisdale, James G Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0141706