Opposite Roles of Furin and PC5A in N-Cadherin Processing
We recently demonstrated that lack of Furin-processing of the N-cadherin precursor (proNCAD) in highly invasive melanoma and brain tumor cells results in the cell-surface expression of a nonadhesive protein favoring cell migration and invasion in vitro. Quantitative polymerase chain reaction analys...
Main Authors: | Deborah Maret, Mohamad Seyed Sadr, Emad Seyed Sadr, David R Colman, Rolando F Del Maestro, Nabil G Seidah |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-10-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558612800200 |
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