TRPV4 Mediates Acute Bladder Responses to Bacterial Lipopolysaccharides

TRPV4 Mediates Acute Bladder Responses to Bacterial Lipopolysaccharides

Urinary tract infections (UTI) affect a large proportion of the population, causing among other symptoms, more frequent and urgent micturition. Previous studies reported that the gram-negative bacterial wall component lipopolysaccharides (LPS) trigger acute epithelial and bladder voiding responses,...

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Bibliographic Details
Main Authors: Yeranddy A. Alpizar, Pieter Uvin, Robbe Naert, Jan Franken, Silvia Pinto, Alicia Sanchez, Thomas Gevaert, Wouter Everaerts, Thomas Voets, Dirk De Ridder, Karel Talavera
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
LPS
TRPV4
bladder
urothelial cells
cystitis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00799/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00799/full

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