Somatostatin Analogue Treatment Primarily Induce miRNA Expression Changes and Up-Regulates Growth Inhibitory miR-7 and miR-148a in Neuroendocrine Cells

Somatostatin Analogue Treatment Primarily Induce miRNA Expression Changes and Up-Regulates Growth Inhibitory miR-7 and miR-148a in Neuroendocrine Cells

Somatostatin (SST) analogues are used to control the proliferation and symptoms of neuroendocrine tumors (NETs). MicroRNAs (miRNA) are small non-coding RNAs that modulate posttranscriptional gene expression. We wanted to characterize the miRNAs operating under the control of SST to elucidate to what...

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Bibliographic Details
Main Authors: Kristina B. V. Døssing, Christina Kjær, Jonas Vikeså, Tina Binderup, Ulrich Knigge, Michael D. Culler, Andreas Kjær, Birgitte Federspiel, Lennart Friis-Hansen
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Genes
Subjects:
somatostatin analogues
neuroendocrine tumors
cancer
miRNAs
miR-148a
miR-7
let-7
Online Access:http://www.mdpi.com/2073-4425/9/7/337

Internet

http://www.mdpi.com/2073-4425/9/7/337

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