The Prolyl Isomerase Pin1 Controls Lipopolysaccharide-Induced Priming of NADPH Oxidase in Human Neutrophils

The Prolyl Isomerase Pin1 Controls Lipopolysaccharide-Induced Priming of NADPH Oxidase in Human Neutrophils

Production of superoxide anion and other reactive oxygen species (ROS) by neutrophils has a vital role in host defense against microbes. However, over-production can induce cell injury participating to inflammation. Superoxide anion is produced by the phagocyte NADPH oxidase/NOX2, a multicomponent e...

Full description

Bibliographic Details
Main Authors: Min Liu, Samia Bedouhene, Margarita Hurtado-Nedelec, Coralie Pintard, Pham My-chan Dang, Shiyuan Yu, Jamel El-Benna
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
neutrophils
LPS
Pin1
NADPH oxidase
NOX2
priming
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02567/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02567/full

Similar Items