Telomeres and replicative cellular aging of the human placenta and chorioamniotic membranes

Telomeres and replicative cellular aging of the human placenta and chorioamniotic membranes

Abstract Recent hypotheses propose that the human placenta and chorioamniotic membranes (CAMs) experience telomere length (TL)-mediated senescence. These hypotheses are based on mean TL (mTL) measurements, but replicative senescence is triggered by short and dysfunctional telomeres, not mTL. We meas...

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Bibliographic Details
Main Authors: Tsung-Po Lai, Mark Simpson, Krunal Patel, Simon Verhulst, Jungsik Noh, Natalie Roche, Debra Heller, George Guirguis, Jerry W. Shay, Utz Herbig, Abraham Aviv
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84728-2

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https://doi.org/10.1038/s41598-021-84728-2

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