Identification and characterization of calcium sparks in cardiomyocytes derived from human induced pluripotent stem cells.

Identification and characterization of calcium sparks in cardiomyocytes derived from human induced pluripotent stem cells.

INTRODUCTION: Ca2+ spark constitutes the elementary units of cardiac excitation-contraction (E-C) coupling in mature cardiomyocytes. Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes are known to have electrophysiological properties similar to mature adult cardiomyocytes. However, i...

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Bibliographic Details
Main Authors: Guang Qin Zhang, Heming Wei, Jun Lu, Philip Wong, Winston Shim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3567046?pdf=render

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http://europepmc.org/articles/PMC3567046?pdf=render

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