Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients

Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients

Background With immunotherapy gaining increasing approval for treatment of different tumor types, scientists rely on cutting edge methods for the monitoring of immune responses and biomarker development in patients. Due to the lack of tools to efficiently detect rare circulating human tumor-specific...

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Bibliographic Details
Main Authors: Pedro J Romero, Daniel E Speiser, Camilla Jandus, Alexandre Harari, Julien Schmidt, Philippe Guillaume, Amélie Cachot, Georg Alexander Rockinger, Margaux Saillard, Georges Coukos
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000435.full

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https://jitc.bmj.com/content/8/1/e000435.full

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