Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model

Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model

Parkinson’s disease (PD) is a progressive neurodegenerative disorder, primarily affecting dopaminergic neurons in the substantia nigra. There is currently no cure for PD and present medications aim to alleviate clinical symptoms, thus prevention remains the ideal strategy to reduce the prevalence of...

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Bibliographic Details
Main Authors: Imène Achour, Anne-Marie Arel-Dubeau, Justine Renaud, Manon Legrand, Everaldo Attard, Marc Germain, Maria-Grazia Martinoli
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
oleuropein
polyphenol
neuroprotection
neurodegeneration
oxidative stress
cellular death
authophagy
Parkinson’s disease
Online Access:http://www.mdpi.com/1422-0067/17/8/1293

Internet

http://www.mdpi.com/1422-0067/17/8/1293

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