L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease
There is strong evidence that intracellular calcium dysregulation plays an important pathological role in Alzheimer's disease, and specifically that beta amyloid may induce increases in intracellular calcium and lead to neuronal cell dysfunction and death. Here we investigated the feasibility o...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-01-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996110002925 |