HER2-Targeted Immunotherapy and Combined Protocols Showed Promising Antiproliferative Effects in Feline Mammary Carcinoma Cell-Based Models

HER2-Targeted Immunotherapy and Combined Protocols Showed Promising Antiproliferative Effects in Feline Mammary Carcinoma Cell-Based Models

Feline mammary carcinoma (FMC) is a highly prevalent tumor, showing aggressive clinicopathological features, with HER2-positive being the most frequent subtype. While, in human breast cancer, the use of anti-HER2 monoclonal antibodies (mAbs) is common, acting by blocking the extracellular domain (EC...

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Bibliographic Details
Main Authors: Andreia Gameiro, Catarina Nascimento, Jorge Correia, Fernando Ferreira
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
feline mammary carcinoma
HER2
monoclonal antibodies
combined therapies
tyrosine kinase inhibitors
feline <i>her2</i> mutations
Online Access:https://www.mdpi.com/2072-6694/13/9/2007

Internet

https://www.mdpi.com/2072-6694/13/9/2007

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