Effect of gonadectomy and estradiol on the expression of insulin signaling cascade genes in female and male mice

A positive effect of estradiol on insulin sensitivity has been shown for females and males. Insulin sensitivity is higher in females than in males, and males show a greater tendency to develop metabolic disorders. It is believed that these sex differences are due to a protective effect of estradiol...

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Bibliographic Details
Main Authors: T. V. Iakovleva, N. E. Kostina, E. N. Makarova, N. M. Bazhan
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2020-07-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
Online Access:https://vavilov.elpub.ru/jour/article/view/2652