DJ-1 Protects Pancreatic Beta Cells from Cytokine- and Streptozotocin-Mediated Cell Death.

A hallmark feature of type 1 and type 2 diabetes mellitus is the progressive dysfunction and loss of insulin-producing pancreatic beta cells, and inflammatory cytokines are known to trigger beta cell death. Here we asked whether the anti-oxidant protein DJ-1 encoded by the Parkinson's disease g...

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Bibliographic Details
Main Authors: Deepak Jain, Gesine Weber, Daniel Eberhard, Amir E Mehana, Jan Eglinger, Alena Welters, Barbara Bartosinska, Kay Jeruschke, Jürgen Weiss, Günter Päth, Hiroyoshi Ariga, Jochen Seufert, Eckhard Lammert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4589499?pdf=render