Increased biogenesis of glucagon-containing secretory granules and glucagon secretion in BIG3-knockout mice

Objective: Although both insulin and glucagon are intimately involved in the regulation of glucose homeostasis, the intrinsic control of glucagon secretion, including the biogenesis and exocytosis of glucagon-containing granules, is far less understood compared with that of insulin. As Brefeldin A-i...

Full description

Bibliographic Details
Main Authors: Hongyu Li, Tao Liu, Joy Lim, Natalia V. Gounko, Wanjin Hong, Weiping Han
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877815000022