Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of <i>K<sub>Ca</sub>2.x</i> and <i>K<sub>Ca</sub>3.1</i> Channels

Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of <i>K<sub>Ca</sub>2.x</i> and <i>K<sub>Ca</sub>3.1</i> Channels

The aim of this study was to investigate the hemodynamic effects of SKA-31, an activator of the small (<i>K<sub>Ca</sub>2.x</i>) and intermediate (<i>K<sub>Ca</sub>3.1</i>) conductance calcium-activated potassium channels, and to evaluate its influence...

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Bibliographic Details
Main Authors: Monika Kloza, Marta Baranowska-Kuczko, Marek Toczek, Magdalena Kusaczuk, Olga Sadowska, Irena Kasacka, Hanna Kozłowska
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
SHR
hypertension
SKA-31
<i>K<sub>Ca</sub>3.1</i>/<i>K<sub>Ca</sub>2.3</i>-EDH–dilator system
K<sub>IR</sub>
Na<sup>+</sup>/K<sup>+</sup>-ATP-ase
Online Access:https://www.mdpi.com/1422-0067/20/17/4118

Internet

https://www.mdpi.com/1422-0067/20/17/4118

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