Baicalin attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A2A receptor-induced SDF-1/CXCR4/PI3K/AKT signaling
Abstract Background Baicalin, an important flavonoid in Scutellaria baicalensis Georgi extracts, exerts a variety of pharmacological effects. In this study, we explored the effects of baicalin on chronic hypoxia-induced pulmonary arterial hypertension (PAH) and investigated the mechanism underlying...
Main Authors: | Xiaoying Huang, Peiliang Wu, Feifei Huang, Min Xu, Mayun Chen, Kate Huang, Guo-ping Li, Manhuan Xu, Dan Yao, Liangxing Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-08-01
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Series: | Journal of Biomedical Science |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12929-017-0359-3 |
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