Extensive Therapeutic Drug Monitoring of Colistin in Critically Ill Patients Reveals Undetected Risks

Extensive Therapeutic Drug Monitoring of Colistin in Critically Ill Patients Reveals Undetected Risks

(1) Background: With the rise of multi-/pan-drug resistant (MDR/PDR) pathogens, the less utilized antibiotic Colistin has made a comeback. Colistin fell out of favor due to its small therapeutic range and high potential for toxicity. Today, it is used again as a last resort substance in treating MDR...

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Bibliographic Details
Main Authors: Stefan Felix Ehrentraut, Stefan Muenster, Stefan Kreyer, Nils Ulrich Theuerkauf, Christian Bode, Folkert Steinhagen, Heidi Ehrentraut, Jens-Christian Schewe, Matthias Weber, Christian Putensen, Thomas Muders
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Microorganisms
Subjects:
colistin
sepsis
colistin methanosulfate
therapeutic drug monitoring
intensive care medicine
renal failure
polymyxin e
acinetobacter baumannii
carbapenem resistant
Online Access:https://www.mdpi.com/2076-2607/8/3/415

Internet

https://www.mdpi.com/2076-2607/8/3/415

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