The pseudogene derived from long non-coding RNA DUXAP10 promotes colorectal cancer cell growth through epigenetically silencing of p21 and PTEN

Abstract Recently, substantial evidence has demonstrated that pseudogene derived lncRNAs are crucial regulators of cancer development and progression. DUXAP10,a pseudogene derived long non-coding RNA(lncRNA), is overexpression in colorectal cancer (CRC), but its expression pattern, biological functi...

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Bibliographic Details
Main Authors: Yifan Lian, Yetao Xu, Chuanxing Xiao, Rui Xia, Huangbo Gong, Peng Yang, Tao Chen, Dongdong Wu, Zeling Cai, Jianping Zhang, Keming Wang
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07954-7