Glycine Protects against Hypoxic-Ischemic Brain Injury by Regulating Mitochondria-Mediated Autophagy via the AMPK Pathway

Hypoxic-ischemic encephalopathy (HIE) is detrimental to newborns and is associated with high mortality and poor prognosis. Thus, the primary aim of the present study was to determine whether glycine could (1) attenuate HIE injury in rats and hypoxic stress in PC12 cells and (2) downregulate mitochon...

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Bibliographic Details
Main Authors: Chen-chen Cai, Jiang-hu Zhu, Li-xia Ye, Yuan-yuan Dai, Ming-chu Fang, Ying-ying Hu, Shu-lin Pan, Si Chen, Pei-jun Li, Xiao-qin Fu, Zhen-lang Lin
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/4248529