Dental follicle cell differentiation towards periodontal ligament-like tissue in a self-assembly three-dimensional organoid model

Periodontitis remains an unsolved oral disease, prevalent worldwide and resulting in tooth loss due to dysfunction of the periodontal ligament (PDL), a tissue connecting the tooth root with the alveolar bone. A scaffold-free three-dimensional (3D) organoid model for in vitro tenogenesis/ligamentogen...

Full description

Bibliographic Details
Main Authors: J Chu, O Pieles, CG Pfeifer, V Alt, C Morsczeck, D Docheva
Format: Article
Language:English
Published: AO Research Institute Davos 2021-07-01
Series:European Cells & Materials
Subjects:
Online Access:https://www.ecmjournal.org/papers/vol042/pdf/v042a02.pdf