Role of peripheral 5-HT1D, 5-HT3 and 5-HT7 receptors in the mechanical allodynia induced by serotonin in mice

Role of peripheral 5-HT1D, 5-HT3 and 5-HT7 receptors in the mechanical allodynia induced by serotonin in mice

Serotonin (5-HT) acts as a neurotransmitter in the central nervous system (CNS) and as a mediator released by enterochromaffin cells to regulate intestinal motility. However, this amine also plays an important role as an inflammatory mediator and induces phenotypic changes of nociceptors. Despite th...

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Bibliographic Details
Main Authors: Elias B. Nascimento, Jr., Thiago R.L. Romero, Marcela M.G.B. Dutra, Bernd L. Fiebich, Igor D.G. Duarte, Márcio M. Coelho
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Pain
Allodynia
Serotonin
Carrageenan
5-HT receptors
Antinociception
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220314037

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220314037

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