Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells.

Human cytomegalovirus (HCMV) infection is one of the leading prenatal causes of congenital mental retardation and deformities world-wide. Access to cultured human neuronal lineages, necessary to understand the species specific pathogenic effects of HCMV, has been limited by difficulties in sustainin...

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Bibliographic Details
Main Authors: Leonardo D'Aiuto, Roberto Di Maio, Brianna Heath, Giorgio Raimondi, Jadranka Milosevic, Annie M Watson, Mikhil Bamne, W Tony Parks, Lei Yang, Bo Lin, Toshio Miki, Jocelyn Danielle Mich-Basso, Ravit Arav-Boger, Etienne Sibille, Sarven Sabunciyan, Robert Yolken, Vishwajit Nimgaonkar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3507916?pdf=render