Preinvasive Colorectal Lesions of African Americans Display an Immunosuppressive Signature Compared to Caucasian Americans

Preinvasive Colorectal Lesions of African Americans Display an Immunosuppressive Signature Compared to Caucasian Americans

BackgroundAfrican Americans (AAs) have higher colorectal cancer (CRC) incidence and mortality rate than Caucasian Americans (CAs). Recent studies suggest that immune responses within CRCs contribute to the disparities. If racially distinct immune signatures are present in the early phases of carcino...

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Bibliographic Details
Main Authors: Kristin Wallace, Georges J. Nahhas, Christine Bookhout, David N. Lewin, Chrystal M. Paulos, Nana Nikolaishvili-Feinberg, Stephanie M. Cohen, Silvia Guglietta, Ali Bakhtiari, E. Ramsay Camp, Elizabeth G. Hill, John A. Baron, Jennifer D. Wu, Alexander V. Alekseyenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
race
disparities
colorectal adenomas
immune infiltrate
immune cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.659036/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.659036/full

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