Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease

Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease

Abstract Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity. We hypothesize that serum cathelicidin correlates with mucosal disease activity, strictur...

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Bibliographic Details
Main Authors: Diana Hoang-Ngoc Tran, Jiani Wang, Christina Ha, Wendy Ho, S. Anjani Mattai, Angelos Oikonomopoulos, Guy Weiss, Precious Lacey, Michelle Cheng, Christine Shieh, Caroline C. Mussatto, Samantha Ho, Daniel Hommes, Hon Wai Koon
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Gastroenterology
Subjects:
Biomarkers
Complications of IBD
Serologic testing
Prognosis
Mucosal disease activity
Online Access:http://link.springer.com/article/10.1186/s12876-017-0619-4

Internet

http://link.springer.com/article/10.1186/s12876-017-0619-4

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