Pseudokinases: From Allosteric Regulation of Catalytic Domains and the Formation of Macromolecular Assemblies to Emerging Drug Targets

Pseudokinases are a member of the kinase superfamily that lack one or more of the canonical residues required for catalysis. Protein pseudokinases are widely distributed across species and are present in proteins that perform a great diversity of roles in the cell. They represent approximately 10% t...

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Bibliographic Details
Main Authors: Andrada Tomoni, Jonathan Lees, Andrés G. Santana, Victor M. Bolanos-Garcia, Agatha Bastida
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/9/9/778