In Silico Identification of Potential Inhibitor Against a Fungal Histone Deacetylase, RPD3 from <i>Magnaporthe Oryzae</i>

Histone acetylation and deacetylation play an essential role in the epigenetic regulation of gene expression. Histone deacetylases (HDAC) are a group of zinc-binding metalloenzymes that catalyze the removal of acetyl moieties from lysine residues from histone tails. These enzymes are well known for...

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Bibliographic Details
Main Authors: Gnanendra Shanmugam, Taehyeon Kim, Junhyun Jeon
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/11/2075