Characterization of rheumatoid arthritis subtypes using symptom profiles, clinical chemistry and metabolomics measurements.

OBJECTIVE: The aim is to characterize subgroups or phenotypes of rheumatoid arthritis (RA) patients using a systems biology approach. The discovery of subtypes of rheumatoid arthritis patients is an essential research area for the improvement of response to therapy and the development of personalize...

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Main Authors: Herman A van Wietmarschen, Weidong Dai, Anita J van der Kooij, Theo H Reijmers, Yan Schroën, Mei Wang, Zhiliang Xu, Xinchang Wang, Hongwei Kong, Guowang Xu, Thomas Hankemeier, Jacqueline J Meulman, Jan van der Greef
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3440441?pdf=render