Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway

Oxidative stress-induced dysfunction or apoptosis in retinal pigment epithelial (RPE) cells is an important cause of dry age-related macular degeneration (AMD). Although phillyrin has been shown to exert significant antioxidant effects, the underlying mechanism of action remains unclear. The purpose...

Full description

Bibliographic Details
Main Authors: Yuanyuan Du, Longtai You, Boran Ni, Na Sai, Wenping Wang, Mingyi Sun, Rui Xu, Yu Yao, Zhiqin Zhang, Changhai Qu, Xingbin Yin, Jian Ni
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/2684672