Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway
Oxidative stress-induced dysfunction or apoptosis in retinal pigment epithelial (RPE) cells is an important cause of dry age-related macular degeneration (AMD). Although phillyrin has been shown to exert significant antioxidant effects, the underlying mechanism of action remains unclear. The purpose...
Main Authors: | Yuanyuan Du, Longtai You, Boran Ni, Na Sai, Wenping Wang, Mingyi Sun, Rui Xu, Yu Yao, Zhiqin Zhang, Changhai Qu, Xingbin Yin, Jian Ni |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
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Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2020/2684672 |
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